Defal Tablet contains 30mg of Deflazacort, a prescription-strength corticosteroid used as an anti-inflammatory and immunosuppressant medication. This steroid therapy effectively treats various conditions responsive to corticosteroid intervention while offering advantages over traditional oral steroids.
Uses
Defal 30mg is prescribed under medical guidance for severe allergies and asthma, certain autoimmune disorders, chronic obstructive pulmonary disease (COPD), and nephrotic syndrome cases unresponsive to other medications. It’s particularly effective for inflammatory conditions requiring systemic corticosteroid therapy.
Benefits
- Provides equal anti-inflammatory power at lower doses than prednisolone
- Reduces risk of bone density loss during prolonged steroid use
- Decreases likelihood of causing obesity, high blood sugar, or salt retention
- Offers convenient once-daily dosing for improved patient adherence
- Demonstrates better safety profile compared to other oral corticosteroids
- Effective for multiple inflammatory and immune-mediated conditions
- Reduces inflammation and suppresses overactive immune responses
- Provides symptom relief for various steroid-responsive conditions
How It Works
Defal works by mimicking cortisol, a natural hormone produced by the adrenal glands. Deflazacort binds to glucocorticoid receptors in cells, reducing inflammation by inhibiting inflammatory mediators and suppressing immune system activity. This mechanism helps control excessive inflammatory responses while maintaining therapeutic effectiveness.
Dosage
Patient Category | Standard Dosage | Maximum Daily Dosage |
---|---|---|
Adults | 30-36mg once daily | 90mg daily |
Elderly | 30mg once daily | 60mg daily |
Take Defal in the morning with food to reduce stomach irritation. Strictly follow medical advice and tapering protocols when discontinuing.
Duration of Action
Defal begins working within 1-2 hours of administration. Peak effects occur within 4-6 hours and last approximately 24 hours. For chronic conditions, therapeutic benefits may take several days to weeks to fully manifest. The medication’s effects gradually diminish over 24-36 hours after the last dose.
Side Effects
Common side effects include increased appetite, mild mood changes, and temporary fluid retention. Some patients may experience stomach upset, difficulty sleeping, or increased susceptibility to infections. Long-term use may cause weight gain, elevated blood pressure, or blood sugar changes, though these occur less frequently than with other corticosteroids.
Warning
Never discontinue Defal abruptly without medical supervision as this can cause dangerous adrenal insufficiency. Immediately consult your doctor if experiencing vision changes, muscle weakness, loss of appetite, or severe tiredness. Long-term use requires regular monitoring of blood pressure, blood sugar, and bone density.
Pregnancy and Breastfeeding
Defal should be used during pregnancy only when benefits clearly outweigh potential risks to the developing fetus. Corticosteroids can cross the placenta and may affect fetal development. Deflazacort passes into breast milk in small amounts. Consult healthcare provider before taking during pregnancy or breastfeeding.
Interaction
- May reduce effectiveness of vaccines and increase infection risk
- Possible interaction with anticoagulants, increasing bleeding risk
- May alter blood sugar control when used with diabetes medications
- Potential interaction with certain antifungal medications
- Could enhance effects of diuretics, leading to electrolyte imbalances
- May reduce effectiveness of some antibiotics
Precaution
Use with caution in patients with diabetes, hypertension, osteoporosis, or history of psychiatric disorders. Avoid live vaccines during treatment. Regular monitoring of blood pressure, blood sugar, and bone density is recommended for long-term use. Inform all healthcare providers about Defal use before procedures or surgeries.
Important Information
Defal is a prescription medication requiring careful medical supervision. Do not share with others or use for conditions not prescribed. Store at room temperature away from moisture and heat. Carry medical identification indicating corticosteroid use. Report any signs of infection promptly as the medication may mask symptoms while suppressing immune response.
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Customer questions & answers
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Can I take piriton after taking defal 30mg?
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Q Can I take piriton after taking defal 30mg? answer nowAsked by Francis on October 3, 2024 7:11 pmA
Hi Francis,
Yes, you can generally take Piriton after Defal 30mg, but both can cause drowsiness. If you're taking Defal 30mg for a specific condition (like asthma, severe allergies, or an autoimmune disease), please ensure that Piriton is appropriate for you, as both medications can affect your immune system. It's best to check with your doctor or pharmacist to ensure it's safe for you.
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